Name: PDGF BB Yeast Recombinant Protein
Price: Inquiry

- Overview
  - PDGF-BB is purified by proprietary chromatographic techniques. PDGF-BB is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two splice variants have been identified for this gene.
    
    Please contact us at for specific academic pricing.
- Properties
  - Protein Name
    
    Glioma-derived growth factor, GDGF, Osteosarcoma-derived Growth Factor, ODGF, SIS, SSV, PDGF2, c-sis, FLJ12858, PDGF-BB, PDGF B-chain, Platelet-derived growth factor beta polypeptide, Becaplermin.
    
    Source
    
    Saccharomyces cerevisiae
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greater than 98.0% as determined by SDS-PAGE.
    
    Formulation
    
    The PDGF-BB was lyophilized from 0.2µm filtered solution in 20mM sodium phosphate in absence of any carrier protein.
    
    Storage
    
    Lyophilized Platelet-derived Growth Factor BB although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution PDGF BB should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.
- Applications
  - Application Description
    
    It is recommended to reconstitute the lyophilized Platelet-derived Growth Factor-BB in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. The ED50, as measured by its ability to stimulate proliferation of mouse 3T3 fibroblasts is typically 1 ng/ml, corresponding to a Specific Activity of 1,000,000IU/mg.

PDGF BB Yeast Recombinant Protein

PDGF BB Yeast Recombinant Protein

We Also Recommend

mPDGF BB Recombinant Protein

PDGFD Recombinant Protein

rPDGF BB Recombinant Protein