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Overview
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Background
The protein encoded by this gene interacts with poly(A)-binding protein and with the cap-binding complex eIF4A. It is involved in translational initiation and protein biosynthesis.Among its related pathways are Deadenylation-dependent mRNA decay and Gene Expression. Overexpression of this gene in COS7 cells stimulates translation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. Gene Ontology (GO) annotations related to this gene include RNA binding and translation activator activity. An important paralog of this gene is CTIF.
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