OX40 Mouse Monoclonal Antibody

OX40 Mouse Monoclonal Antibody

Catalog Number:
A001452098ZEN
Mfr. No.:
Zen-222573
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      • Overview
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          Background

          The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.

      • Properties
        • Host
          mouse
          Isotype
          Mouse IgG1
          Reactivity
          human
          Immunogen
          Purified recombinant fragment of human CD134 expressed in E. Coli.
          Purification
          Affinity Purified
          Conjugate
          Unconjugated
          Formulation
          Purified antibody in PBS with 0.05% sodium azide
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
          Antigen
          (Gene ID:7293; UniProt:P43489)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          IHC-P; FC; ELISA
        • Application Dilutions
          IHC 1/100-1/200
          FC 1/50-1/100
          ELISA 1/10000

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