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Overview
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Calculated MW: 104kDa/107kDa/108kDa
Observed MW: 109kDaPlease contact us at for specific academic pricing.
Background
The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1).
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