Nonyl b-D-glucopyranoside

- Overview
  - Nonyl β-D-glucopyranoside is an alkylglycoside non-ionic mild detergent used for cell lysis and membrane protein isolation. As it is uncharged it is unlikely to cause protein denaturation or refolding issues, allowing for the isolation of intact macromolecular complexes without affecting protein-protein interactions. Nonyl β-D-glucopyranoside is useful for the solubilization and crystallization of many biological membrane proteins and isolation of membrane-bound proteins. It has also been used for enantiomeric separation by capillary electrophoresis. Nonyl β-D-glucopyranoside is also known as B-Nonylglucoside or Nonyl D-glucoside and has an aggregation number of 133. It is dialyzable from membrane protein preparations and has a Critical Micelle Concentration (CMC) of 6.5mM.
    
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- Properties
  - CAS Number
    
    69984-73-2
    
    Molecular Formula
    
    C15H30O6
    
    Molecular Weight
    
    306.4 g/mol
    
    MDL Number
    
    MFCD00063300
    
    Note
    
    There is no hazardous surcharge associated with this product.
    There is no special packaging charge associated with this product.
    
    * For research use only. Not for human or veterinary use
- Reference
  - deGrip et al (1979). Synthesis and properties of alkylglucosides with mild detergent action: improved synthesis and purification of β-1-octyl-, -nonyl-, and -decyl-glucose. Synthesis of β-1-undecylglucose and β-1-dodecylmaltose. Chemistry and Physics of Lipids 23(4):321-335.
    Chung et al (1989). The lyotropic liquid crystal properties of n-octyl 1-O-beta-D-glucopyranoside and related n-alkyl pyranosides. Biochimica et biophysica acta 985(3):300–306.
    Mechref et al (1997) Capillary electrophoresis of herbicides II. Evaluation of alkylglucoside chiral surfactants in the enantiomeric separation of phenoxy acid herbicides. Journal of Chromatography A 757(1–2):263-273.
    Otsuka et al (2000) Enantiomer separation of drugs by micellar electrokinetic chromatography using chiral surfactants. Journal of Chromatography A 875(1–2) 163-178.

MSDS

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Specification

Nonyl b-D-glucopyranoside

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