NFKB1 Polyclonal Antibody (0.84 mg/mL) for IHC, ELISA

NFKB1 Polyclonal Antibody (0.84 mg/mL) for IHC, ELISA

Catalog Number:
A001507838RED
Mfr. No.:
RD252132A
Price:
$253
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      • Overview
        • Gene Accession: BC051765

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          Background

          This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human
          Immunogen
          Fusion protein of human NFKB1
          Purification
          Antigen affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          0.84 mg/mL
          Antigen
          DKFZp686C01211, DNA binding factor KBF1, DNA binding factor KBF1 EBP1, DNA-binding factor KBF1, EBP 1, EBP-1, EBP1, KBF1, MGC54151, nf b, NF kappa B, NF kappaB, NF kappabeta, NF kB1, NFkappaB, NFKB 1, NFKB p105, NFKB p50, Nfkb1, NFKB1, Nuclear factor kappa B DNA binding subunit, Nuclear factor kappa-B, subunit 1, Nuclear factor NF kappa B p105 subunit, Nuclear factor NF kappa B p50 subunit, Nuclear factor NF-kappa-B p50 subunit, Nuclear factor of kappa light chain gene enhancer in B cells 1, Nuclear factor of kappa light polypeptide gene enhancer in B cells 1, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105, p50, p84/NF-kappa-B1 p98, Transcription factor NFKB1 (UniProt:P19838)

          * For reference only.

      • Applications
        • Application
          IHC; ELISA
        • Application Dilutions
          IHC 1:50-1:200
          ELISA 1:5000-1:10000

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