Neurophysin I Rabbit Polyclonal Antibody

Neurophysin I Rabbit Polyclonal Antibody

Catalog Number:
A001451896ZEN
Mfr. No.:
Zen-370192
Price:
  • Size:
    100μl
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      • Overview
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          Background

          Neurophysin I (NPI) and neurophysin II (NPII) function as carrier proteins for oxytocin and vasopressin, respectively. Oxytocin is a pituitary hormone which induces uterine contractions during childbirth and the ejection of milk from the mammary glands during nursing. Vasopressin is involved in the metabolism of water and electrolytes and has been identified as a vasoconstrictor. Both neurophysin genes exist as three exons, with each exon encoding a functional protein domain. Studies show that the identically conserved middle region (exon B) is involved in NP-NP homodimer formation as well as being the site for the glycine 17 to valine point mutation responsible for familial diabetes insipidus.

      • Properties
        • Host
          rabbit
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Synthetic peptide corresponding to Human Neurophysin I.
          Purification
          Affinity Purified
          Conjugate
          Unconjugated
          Formulation
          1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
          Antigen
          (Gene ID:5020; UniProt:P01178)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          WB; IHC-P
        • Application Dilutions
          WB 1/500-1/1000
          IHC 1/50-1/200

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