Nampt (2E11) Mouse Monoclonal Antibody

Nampt (2E11) Mouse Monoclonal Antibody

Catalog Number:
A001451881ZEN
Mfr. No.:
Zen-220195
Price:
  • Size:
    100μl
    Quantity:
    Add to Cart:
      • Overview
        • Please contact us at for specific academic pricing.

          Background

          PBEF1: nicotinamide phosphoribosyltransferase. This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.

      • Properties
        • Host
          mouse
          Isotype
          IgG1
          Reactivity
          human
          Clone
          2E11-F7-G3
          Immunogen
          Purified recombinant fragment of PBEF1 expressed in E. Coli.
          Purification
          Ascitic Fluid
          Conjugate
          Unconjugated
          Formulation
          Ascitic fluid containing 0.03% sodium azide.
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
          Molecular Weight
          Calculated MW: 56 kDa; Observed MW: 56 kDa
          Antigen
          (Gene ID:10135; UniProt:P43490)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1/500-1/1000

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