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Overview
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Calculated MW: 19kDa/46kDa/60kDa/63kDa
Observed MW: 70KDaPlease contact us at for specific academic pricing.
Background
This gene encodes a transcription factor that is required for central nervous system myelination and may regulate oligodendrocyte differentiation. It is thought to act by increasing the expression of genes that effect myelin production but may also directly promote myelin gene expression. Loss of a similar gene in mouse models results in severe demyelination. Alternative splicing results in multiple transcript variants.
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