Mouse anti-Mono-Methyl-P53 ( Lys370 ) Monoclonal Antibody

Mouse anti-Mono-Methyl-P53 ( Lys370 ) Monoclonal Antibody

Catalog Number:
A001079696RED
Mfr. No.:
RD86238A
Price:
$253
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      • Overview
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          Background

          The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.

      • Properties
        • Host
          mouse
          Antibody Type
          monoclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Synthetic Peptide
          Purification
          Protein A purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 50% glycerol, pH7.4
          Storage
          Store at -20°C. Avoid repeated freeze / thaw cycles.
          Concentration
          1mg/mL
          Antigen
          Antigen NY-CO-13; BCC7; Cellular tumor antigen p53; FLJ92943; LFS1; Mutant tumor protein 53; p53; p53 tumor suppressor; P53; Phosphoprotein p53; Tp53; Transformation related protein 53; TRP53; Tumor protein 53; Tumor protein p53; Tumor suppressor p53 (Gene ID:7157; UniProt:P04637)

          * For research use only.

      • Applications
        • Application
          IHC (paraffin)

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