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Overview
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Calculated MW: 46kDa/92kDa
Observed MW: 95KDaPlease contact us at for specific academic pricing.
Background
This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described.
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- Properties
- Applications
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Overview