Name: MAPKAPK3 Polyclonal Antibody (0.9 mg/mL) for IHC, ELISA
Price: 253.00 USD

Overview
- Gene Accession: BC001662
  
  Please contact us at for specific academic pricing.
  
  Background
  
  This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation. Alternate splicing results in multiple transcript variants that encode the same protein.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Fusion protein of human MAPKAPK3
  
  Purification
  
  Antigen affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
  
  Storage
  
  Store at -20°C. Avoid freeze-thaw cycles.
  
  Concentration
  
  0.9 mg/mL
  
  Antigen
  
  3pK, anti MAPKAPK3, Chromosome 3p kinase, EC 2.7.11.1, MAP kinase-activated protein kinase 3, MAPK activated protein kinase 3, MAPK-activated protein kinase 3, MAPK3, MAPKAP, MAPKAP kinase 3, MAPKAP-K3, MAPKAP3, MAPKAPK 3, MAPKAPK-3, Mapkapk3, MAPKAPK3, Mitogen activated protein kinase activated protein kinase 3, Mitogen activated protein kinase activated protein kinase, MK-3 (UniProt:Q16644)
  
  * For reference only.