MAPK8IP3 Polyclonal Antibody

MAPK8IP3 Polyclonal Antibody

Catalog Number:
A001506445RED
Mfr. No.:
RD218142A
Price:
$253
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      • Overview
        • Gene Accession: NP055948

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          Background

          The protein encoded by this gene shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart of this gene is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. MAPK8IP3 (Mitogen-Activated Protein Kinase 8 Interacting Protein 3) is a Protein Coding gene. Among its related pathways are MAPK signaling pathway and Arf6 trafficking events. GO annotations related to this gene include kinesin binding and receptor signaling complex scaffold activity. An important paralog of this gene is SPAG9.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human
          Immunogen
          Synthetic peptide of human MAPK8IP3
          Purification
          Antigen affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          1.26 mg/mL
          Antigen
          C-jun-amino-terminal kinase-interacting protein 3, FLJ00027, Homolog of Drosophila Sunday driver 2, JIP-3, JIP3, JIP3, JNK / Stress Activated Protein Kinase Associated Protein 1, JNK Interacting Protein 3, JNK MAP kinase scaffold protein 3, JNK-interacting protein 3, JNK/SAPK associated protein 1, JSAP1, KIAA1066, MAPK8IP3, Mitogen Activated Protein kinase 8 Interacting Protein 3, Mitogen-activated protein kinase 8-interacting protein 3, Syd, SYD2 (UniProt:Q9UPT6)

          * For reference only.

      • Applications
        • Application
          IHC; ELISA
        • Application Dilutions
          IHC 1:40-1:200
          ELISA 1:5000-1:10000

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