MAPK11 Recombinant Protein

MAPK11 Recombinant Protein

Catalog Number:
P001416510ABE
Mfr. No.:
Abe32-3049
Price:
  • Size:
    5 µg
    Quantity:
    Add to Cart:
      • Overview
        • MAPK11 Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 387 amino acids (1-364 a.a.) and having a molecular mass of 43.8kDa. MAPK11 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. MAPK11 belongs to the MAP kinase family and is most associated with p38 MAP kinases (MAPKs). MAPKs are activated mainly as a reaction to cellular stress and inflammatory cytokines, and inhibitors that target the MAPK14 and MAPK11 have demonstrated ability to cure inflammatory disease. MAPK11 cooperates with HDAC3 and Promyelocytic leukemia protein and takes part in a signal transduction pathway which is activated by alterations in the osmolarity of the extracellular environment, by environmental stress, or by cytokines.

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      • Properties
        • Protein Name
          Mitogen-activated protein kinase 11, PRKM11, SAPK2, p38-2, p38Beta, Mitogen-activated protein kinase p38 beta, Stress-activated protein kinase 2b, SAPK2B, MAP kinase 11, MAP kinase p38 beta, MAPK 11, P38BETA2, mitogen-activated protein kinase p38-2
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greater than 90.0% as determined by SDS-PAGE analysis.
          Formulation
          MAPK11 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 2mM DTT, 100mM NaCl and 20% glycerol.
          Storage
          Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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