LPP Mouse Monoclonal Antibody

LPP Mouse Monoclonal Antibody

Catalog Number:
A001451440ZEN
Mfr. No.:
Zen-222433
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      • Overview
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          Background

          LIM domain containing preferred translocation partner in lipoma. The Zyxin family of proteins contains five members, Ajuba, LIMD1, LPP,TRIP6 and Zyxin. LPP (LIM-containing lipoma-preferred partner), a LIM domain-containing scaffolding protein contains three LIM domains at its carboxy terminus, which are preceded by a proline-rich pre-LIM region containing a number of protein interaction domains. LPP, an 80 kDa protein, localizes to sites of cell adhesion, such as focal adhesions and cell-cell contacts,and shuttles to the nucleus where it has transcriptional activation capacity.The human LPP gene maps to chromosomal location 3q28, and preferentially translocates to the HMGIC gene in a subclass of human benign mesenchymal tumors known as lipomas.

      • Properties
        • Host
          mouse
          Isotype
          Mouse IgG1
          Reactivity
          human; mouse; monkey; hamster
          Immunogen
          Purified recombinant fragment of human LPP expressed in E. Coli.
          Purification
          Affinity Purified
          Conjugate
          Unconjugated
          Formulation
          Ascitic fluid containing 0.03% sodium azide.
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
          Molecular Weight
          Calculated MW: 66 kDa;Observed MW: 72 kDa
          Antigen
          (Gene ID:4026; UniProt:Q93052)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          WB; IHC-P; ICC/IF
        • Application Dilutions
          WB 1/500-1/1000
          IHC 1/100-1/200
          IF 1/50-1/200

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