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Overview
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Calculated MW: 12kDa/54kDa/65kDa/66kDa/74kDa/75kDa/77kDa
Observed MW: 75KDaPlease contact us at for specific academic pricing.
Background
LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.
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- Properties
- Applications
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Overview