LIGHT Mouse Monoclonal Antibody

LIGHT Mouse Monoclonal Antibody

Catalog Number:
A001451445ZEN
Mfr. No.:
Zen-222427
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      • Overview
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          Background

          The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported.

      • Properties
        • Host
          mouse
          Isotype
          Mouse IgG2b
          Reactivity
          human; mouse
          Immunogen
          Purified recombinant fragment of human CD258 expressed in E. Coli.
          Purification
          Affinity Purified
          Conjugate
          Unconjugated
          Formulation
          Purified antibody in PBS with 0.05% sodium azide
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
          Molecular Weight
          Calculated MW: 26 kDa
          Antigen
          (Gene ID:8740; UniProt:O43557)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          WB; IHC-P; FC; ELISA
        • Application Dilutions
          WB 1/500-1/1000
          IHC 1/100-1/200
          FC 1/50-1/100
          ELISA 1/10000

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