LEF1 Mouse Monoclonal Antibody

LEF1 Mouse Monoclonal Antibody

Catalog Number:
A001451452ZEN
Mfr. No.:
Zen-222424
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      • Overview
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          Background

          This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.

      • Properties
        • Host
          mouse
          Isotype
          Mouse IgG1
          Reactivity
          human
          Immunogen
          Purified recombinant fragment of human LEF1 expressed in E. Coli.
          Purification
          Affinity Purified
          Conjugate
          Unconjugated
          Formulation
          Purified antibody in PBS with 0.05% sodium azide
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
          Molecular Weight
          Calculated MW: 44 kDa;Observed MW: 44 kDa
          Antigen
          (Gene ID:51176; UniProt:Q9UJU2)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          WB; IHC-P; ELISA
        • Application Dilutions
          WB 1/500-1/1000
          IHC 1/100-1/200
          ELISA 1/10000

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