LC3A (8F5) Mouse Monoclonal Antibody

LC3A (8F5) Mouse Monoclonal Antibody

Catalog Number:
A001451508ZEN
Mfr. No.:
Zen-250310
Price:
  • Size:
    100μl
    Quantity:
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      • Overview
        • Please contact us at for specific academic pricing.

          Background

          Autophagy marker Light Chain 3 (LC3) was originally identified as a subunit of microtubule-associated proteins 1A and 1B (termed MAP1LC3), and subsequently found to contain similarity to the yeast protein Apg8/Aut7/Cvt5 critical for autophagy. Three human LC3 isoforms (LC3A, LC3B, and LC3C) undergo post-translational modifications during autophagy. Cleavage of LC3 at the carboxy terminus immediately following synthesis yields the cytosolic LC3-I form.

      • Properties
        • Host
          mouse
          Isotype
          IgG1
          Reactivity
          human; rat; mouse
          Clone
          8F5-10H1-9A7
          Immunogen
          Purified recombinant protein expressed in E.coli.
          Purification
          Affinity Purified
          Conjugate
          Unconjugated
          Formulation
          Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
          Molecular Weight
          Calculated MW: 14 kDa; Observed MW: 14,16 kDa
          Antigen
          (Gene ID:84557; UniProt:Q9H492)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          WB; IHC-P
        • Application Dilutions
          WB 1/500-1/1000
          IHC 1/50-1/100

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