LATS2 Rabbit Polyclonal Antibody

LATS2 Rabbit Polyclonal Antibody

Catalog Number:
A001451502ZEN
Mfr. No.:
Zen-160914
Price:
  • Size:
    100μl
    Quantity:
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      • Overview
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          Background

          This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.

      • Properties
        • Host
          rabbit
          Isotype
          IgG
          Reactivity
          human; mouse
          Immunogen
          Synthetic peptide of human LATS2
          Purification
          Affinity Purified
          Conjugate
          Unconjugated
          Formulation
          pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
          Antigen
          (Gene ID:26524; UniProt:Q9NRM7)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          IHC-P
        • Application Dilutions
          IHC 1/50-1/100

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