KRT80 Polyclonal Antibody

KRT80 Polyclonal Antibody

Catalog Number:
A001511268RED
Mfr. No.:
RD89659A
Price:
$416
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      • Overview
        • Calculated MW: 133kDa/144kDa/149kDa
          Observed MW: 180kDa

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          Background

          Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene's expression profile shows that it encodes a type II epithelial keratin, although structurally the encoded protein is more like a type II hair keratin. This protein is involved in cell differentiation, localizing near desmosomal plaques in earlier stages of differentiation but then dispersing throughout the cytoplasm in terminally differentiating cells. The type II keratins are clustered in a region of chromosome 12q13. Two transcript variants encoding two different fully functional isoforms have been found for this gene.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Recombinant fusion protein of human KRT80
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% proclin300,50% glycerol,pH7.3.
          Storage
          Store at -20°C Valid for 12 months. Avoid freeze-thaw cycles.
          Concentration
          1mg/mL
          Antigen
          KRT80, KB20 (Gene ID:144501; UniProt:Q6KB66)

          * For reference only.

      • Applications
        • Application
          IF
        • Application Dilutions
          IF 1:50-1:200

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