Name: KIR3DL1 Polyclonal Antibody (1.86 mg/mL) for WB, IHC, ELISA
Price: 253.00 USD

Overview
- Calculated MW: 49 kDa
  Observed MW: Refer to figures
  Gene Accession: BC028206
  
  Please contact us at for specific academic pricing.
  
  Background
  
  Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human
  
  Immunogen
  
  Fusion protein of human KIR3DL1
  
  Purification
  
  Antigen affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
  
  Storage
  
  Store at -20°C. Avoid freeze-thaw cycles.
  
  Concentration
  
  1.86 mg/mL
  
  Antigen
  
  AMB11, CD158 antigen-like family member E, CD158e, CD158e antigen, CD158E1, CD158E1/2, CD158E2, CL11, CL2, HLA-BW4-specific inhibitory NK cell receptor, KI3L1, killer cell immunoglobulin like receptor, Killer cell immunoglobulin like receptor three domains, short cytoplasmic tail, 1, Killer cell immunoglobulin like receptor three domains long cytoplasmic tail 1, Killer cell immunoglobulin-like receptor 3DL1, KIR, KIR antigen 3DL1, KIR G1, Kir3dl1, KIR3DS1, Kirl1, Kirl2, Krl1, MGC119726, MGC119728, MGC126589, MGC126591, MHC class I NK cell receptor, Natural killer associated transcript 3, Natural killer cell inhibitory receptor, Natural killer-associated transcript 3, NK receptor, NK-associated transcript 10, NK-associated transcript 3, NK-associated transcript 3delIg1, NKAT-3, NKAT10, NKAT3, NKB1, NKB1B, p70 killer cell inhibitory receptor, p70 natural killer cell receptor clones CL 2/CL 11, p70 natural killer cell receptor clones CL-2/CL-11, p70 NK receptor CL-2/CL-11 (UniProt:P43629)
  
  * For reference only.

Applications

Application

WB; IHC; ELISA

Application	Dilutions
WB	1:1000-1:5000
IHC	1:50-1:300
ELISA	1:5000-1:10000

KIR3DL1 Polyclonal Antibody (1.86 mg/mL) for WB, IHC, ELISA

KIR3DL1 Polyclonal Antibody (1.86 mg/mL) for WB, IHC, ELISA

Background

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