KCNIP3 Polyclonal Antibody (1.62 mg/mL) for IHC, ELISA

KCNIP3 Polyclonal Antibody (1.62 mg/mL) for IHC, ELISA

Catalog Number:
A001507204RED
Mfr. No.:
RD219200A
Price:
$253
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      • Overview
        • Gene Accession: BC012850

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          Background

          This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described. KCNIP3 (Potassium Voltage-Gated Channel Interacting Protein 3) is a Protein Coding gene. Diseases associated with KCNIP3 include Alzheimer Disease. Among its related pathways are Cardiac conduction and Development Ligand-independent activation of ESR1 and ESR2. GO annotations related to this gene include calcium ion binding and transcription corepressor activity. An important paralog of this gene is KCNIP4.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Fusion protein of human KCNIP3
          Purification
          Antigen affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          1.62 mg/mL
          Antigen
          4933407H12Rik, A type potassium channel modulatory protein 3, A-type potassium channel modulatory protein 3, AI413860, Calsenilin, CSEN, CSEN, DRE antagonist modulator, DRE-antagonist modulator, DREAM, EF hand transcription factor, KCHIP 3, KChIP3, KCNIP 3, Kcnip3, Kv channel interacting protein 3, Kv channel-interacting protein 3, MGC18289, Potassium channel interacting protein 3, R74849 (UniProt:Q9Y2W7)

          * For reference only.

      • Applications
        • Application
          IHC; ELISA
        • Application Dilutions
          IHC 1:50-1:100
          ELISA 1:5000-1:10000

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