JNK3 Mouse Monoclonal Antibody

JNK3 Mouse Monoclonal Antibody

Catalog Number:
A001451251ZEN
Mfr. No.:
Zen-222390
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      • Overview
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          Background

          The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals and are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.

      • Properties
        • Host
          mouse
          Isotype
          Mouse IgG2a
          Reactivity
          human; rat
          Immunogen
          Purified recombinant fragment of human MAPK10 expressed in E. Coli.
          Purification
          Affinity Purified
          Conjugate
          Unconjugated
          Formulation
          Purified antibody in PBS with 0.05% sodium azide
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
          Molecular Weight
          Calculated MW: 53 kDa;Observed MW: 53 kDa
          Antigen
          (Gene ID:5602; UniProt:P53779)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          WB; ELISA
        • Application Dilutions
          WB 1/500-1/1000
          ELISA 1/10000

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