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Overview
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HuS1 is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex. This protein associates with Rad9 and Rad1 to form the 9-1-1 (RAD9-RAD1-HuS1) complex, which localizes to DNA lesions and promotes DNA damage signaling and repair or apoptosis, cell cycle arrest. The trimeric complex is structurally similar to the proliferating cell nuclear antigen (PCNA) sliding clamp and interacts with Rad17 as a clamp-clamp loader pair during the DNA damage response
PRODUCT INFORMATION
Antigen Species: Human
NCBI Accession No: NP_004498.1
RNA Reference Number: NM_004507.3
OMIM Number: 603760
Chromosome Location: 7p13-p12
cDNA size: 843bp
Vector description: This shuttle vector contains the complete ORF. It is inseted BamH I to EcoR I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.Please contact us at for specific academic pricing.
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Overview