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Human Vascular Endothelial Growth Factor-121 (AF)

Human Vascular Endothelial Growth Factor-121 (AF)

Catalog Number:
P001413122ABE
Mfr. No.:
Abe32-12334
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      • Overview

        • Predicted MW: Dimer, 14.1/28.3 kDa (121/242 aa). Vascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF-A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxide-dependent pathways. VEGF-A has several alternatively spliced isoforms, with one being VEGF-121. The VEGF-121 isoform is a secreted protein that acts on receptors VEGFR-1 and VEGFR-2 to modulate endothelial cell function.

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      • Properties
        • Protein Name
          Vascular endothelial growth factor A, Vascular permeability factor, VPF
          Source
          Genetically modified E.coli
          Type
          Recombinant Proteins
          Purification
          Reducing and Non-Reducing SDS PAGE at >= 95%
          Formulation
          Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
          Sterile water at 0.1 mg/mL
          Storage
          Store at -20°C
          Endotoxin
          Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.

          More Information

          UniProt
          P15692-9
          Gene ID
          7422

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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