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Target Information
Target NameSclerostinDatabase LinksSOST_HUMAN ; Reactome: R-HSA-201681 ; Gene ID: 50964About TargetTissue Specificity: Widely expressed at low levels with highest levels in bone, cartilage, kidney, liver, bone marrow and primary osteoblasts differentiated for 21 days. Detected in the subendothelial layer of the aortic intima (at protein level).
Function: Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
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