Human PRSS8 (Protease, Serine 8) CLIA Kit

Prostasin; Channel-Activating Protease 1; Cap1; Serine Protease 8 Cleaved Into - Prostasin Light Chain - Prostasin Heavy Chain

PRSS8_HUMAN ; Reactome: R-HSA-6809371 ; Gene ID: 5652

Tissue Specificity: Found in prostate, liver, salivary gland, kidney, lung, pancreas, colon, bronchus and renal proximal tubular cells. In the prostate gland it may be synthesized in epithelial cells, secreted into the ducts, and excreted into the seminal fluid.

Function: Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the gamma subunits (SCNN1G).