Human PLVAP (Plasmalemma Vesicle Associated Protein) CLIA Kit

Plasmalemma Vesicle-Associated Protein; Fenestrated Endothelial-Linked Structure Protein; Plasmalemma Vesicle Protein 1; Pv-1

PLVAP_HUMAN ; Gene ID: 83483

Tissue Specificity: Expressed in lung, kidney, heart, aorta, placenta, muscle, pituitary gland, adrenals, mammary gland, bladder, lymph node, bone marrow, trachea, digestive tract, liver and tumor-associated endothelium.

Function: Endothelial cell-specific membrane protein involved in the formation of the diaphragms that bridge endothelial fenestrae. It is also required for the formation of stomata of caveolae and transendothelial channels. Functions in microvascular permeability, endothelial fenestrae contributing to the passage of water and solutes and regulating transcellular versus paracellular flow in different organs. Plays a specific role in embryonic development.