Human GP6 (Glycoprotein VI, Platelet) CLIA Kit

Platelet Glycoprotein Vi; Gpvi; Glycoprotein 6

GPVI_HUMAN ; Reactome: R-HSA-114604 ; Gene ID: 51206

Tissue Specificity: Megakaryocytes and platelets.

Function: Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma-chain, the Src kinases (likely FYN or LYN) and SYK, the adapter protein LAT and leads to the activation of PLCG2.