Name: Human Fibroblast Growth Factor-basic 154
Price: Inquiry

- Overview
  - Predicted MW: Monomer, 17.3 kDa (155 aa). Basic fibroblast growth factor (FGF-basic), also known as FGF-2, is expressed by endothelial cells and is a mediator of angiogenesis. FGF-basic also has cardioprotective functions during heart injury. FGF-basic is a critical component for embryonic stem cell culture systems and is necessary for maintaining cells in an undifferentiated state. Recombinant FGF-basic 154 is the full length FGF-basic protein encoded by the human FGF-2 gene. There are no detectable differences in biological activity between FGF-basic 154 and the truncated FGF-basic 147 proteins.
    
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- Properties
  - Protein Name
    
    Basic fibroblast growth factor, Heparin-binding growth factor 2, FGFB
    
    Source
    
    Genetically modified E.coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Reducing and Non-Reducing SDS PAGE at >= 95%
    
    Formulation
    
    Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, 75 mM sodium chloride, pH 8.0
    Sterile water at 0.1 mg/mL
    
    Storage
    
    Store at -20°C
    
    Endotoxin
    
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.
    
    Activity
    
    Biological Activity was determined by 3T3 Proliferation. at <=5 ng/mL; >= 2.0 x 10^5 units/mg (typical ED50 is < 1 ng/mL). Centrifuge vial before opening, Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws. Upon reconstitution, a small amount of visible precipitate can be expected. A 10% overfill has been added to the total material vialed to compensate for this loss.
    
    More Information
    
    UniProt
    
    P09038
    
    Gene ID
    
    2247
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Human Fibroblast Growth Factor-basic 154

Human Fibroblast Growth Factor-basic 154

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