Human F7 (Coagulation Factor VII) CLIA Kit

Coagulation Factor Vii; Proconvertin; Serum Prothrombin Conversion Accelerator; Spca; Eptacog Alfa Cleaved Into - Factor Vii Light Chain - Factor Vii Heavy Chain

Uniprot ID: TNPO1_HUMAN ; Reactome: R-HSA-1368108 ; Gene ID: 2155

Tissue Specificity: Plasma.

Function: Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.