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Overview
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This EXT1 CLIA Kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes.
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Target Information
Target NameExostosin-1; Glucuronosyl-N-Acetylglucosaminyl-Proteoglycan/N-Acetylglucosaminyl-Proteoglycan 4-Alpha-N-Acetylglucosaminyltransferase; Multiple Exostoses Protein 1; Putative Tumor Suppressor Protein Ext1Database LinksUniprot ID: TFPI1_HUMAN ; Reactome: R-HSA-2022928 ; Gene ID: 2131About TargetTissue Specificity: Ubiquitous.
Function: Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor. Required for the exosomal release of SDCBP, CD63 and syndecan.
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