Human EREG (Epiregulin) CLIA Kit

Proepiregulin Cleaved Into - Epiregulin; Epr

Uniprot ID: TCF20_HUMAN ; Reactome: R-HSA-1227986 ; Gene ID: 2069

Tissue Specificity: In normal adults, expressed predominantly in the placenta and peripheral blood leukocytes. High levels were detected in carcinomas of the bladder, lung, kidney and colon.

Function: Ligand of the EGF receptor/EGFR and ERBB4. Stimulates EGFR and ERBB4 tyrosine phosphorylation. Contributes to inflammation, wound healing, tissue repair, and oocyte maturation by regulating angiogenesis and vascular remodeling and by stimulating cell proliferation.