Human Epidermal Growth Factor (AF)

Human Epidermal Growth Factor (AF)

Catalog Number:
P001413108ABE
Mfr. No.:
Abe32-12033
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      • Overview
        • Predicted MW: Monomer, 6.2 kDa (53 aa). Epidermal growth factor (EGF) is a growth factor that stimulates the proliferation, differentiation, and survival of epithelial and epidermal cells. EGF contains three intramolecular disulfide bonds and binds in high affinity to the epidermal growth factor receptor (EGFR). EGF is overexpressed in multiple tumor cell lines and promotes resistance to chemotherapy and radiation treatments.

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      • Properties
        • Protein Name
          Urogastrone
          Source
          Genetically modified E.coli
          Type
          Recombinant Proteins
          Purification
          Reducing and Non-Reducing SDS PAGE at >= 95%
          Formulation
          Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
          Sterile water at 0.1 mg/mL
          Storage
          Store at -20°C
          Endotoxin
          Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.
          Activity
          Biological Activity was determined by 3T3 cell proliferationat <=100 pg/mL; >= 1.0 x 10^7 units/mg (typical ED50 is 10-50 pg/mL). Centrifuge vial before opening, Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws. Upon reconstitution, a small amount of visible precipitate can be expected. A 10% overfill has been added to the total material vialed to compensate for this loss.

          More Information

          UniProt
          Gene ID
          1950

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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