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Overview
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This CPE CLIA Kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes.
Please contact us at for specific academic pricing.
Target Information
Target NameCarboxypeptidase E; Cpe; Carboxypeptidase H; Cph; Enkephalin Convertase; Prohormone-Processing CarboxypeptidaseDatabase LinksUniprot ID: PON3_HUMAN ; Reactome: R-HSA-264876 ; Gene ID: 1363About TargetTissue Specificity: Isoform 2, but not isoform 1, is overexpressed in hepatocellular carcinoma (at protein level), as well as in other tumors, including pheochromocytomas and paragangliomas.
Function: Sorting receptor that directs prohormones to the regulated secretory pathway. Acts also as a prohormone processing enzyme in neuro/endocrine cells, removing dibasic residues from the C-terminal end of peptide hormone precursors after initial endoprotease cleavage.
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