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Overview
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This CFL1 CLIA Kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes.
Please contact us at for specific academic pricing.
Target Information
Target NameCofilin-1; 18 Kda Phosphoprotein; P18; Cofilin - Non-Muscle IsoformDatabase LinksUniprot ID: NGF_HUMAN ; Reactome: R-HSA-114608 ; Gene ID: 1072About TargetTissue Specificity: Widely distributed in various tissues.
Function: Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation. Required for neural tube morphogenesis and neural crest cell migration.
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