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Overview
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This CCKAR CLIA Kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes.
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Target Information
Target NameCholecystokinin Receptor Type A; Cck-A Receptor; Cck-Ar; Cholecystokinin-1 Receptor; Cck1-RDatabase LinksUniprot ID: MEPE_HUMAN ; Reactome: R-HSA-375276 ; Gene ID: 886About TargetFunction: Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
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