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Overview
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This CA4 CLIA Kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes.
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Target Information
Target NameCarbonic Anhydrase 4; Carbonate Dehydratase Iv; Carbonic Anhydrase Iv; Ca-IvDatabase LinksUniprot ID: JAK3_HUMAN ; Reactome: R-HSA-1237044 ; Gene ID: 762About TargetTissue Specificity: Expressed in the endothelium of the choriocapillaris in eyes (at protein level). Not expressed in the retinal epithelium at detectable levels.
Function: Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis. It is essential for acid overload removal from the retina and retina epithelium, and acid release in the choriocapillaris in the choroid.
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