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Overview
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This BPI CLIA Kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes.
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Target Information
Target NameBactericidal Permeability-Increasing Protein; Bpi; Cap 57Database LinksUniprot ID: HIS1_HUMAN ; Reactome: R-HSA-166016 ; Gene ID: 671About TargetTissue Specificity: Restricted to cells of the myeloid series.
Function: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria.this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa.
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- Properties
- Applications
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Overview