Name: Human BMP-2 Recombinant Protein (Animal Free) Lyophilized
Price: 613.00 USD

- Overview
  - Human BMP-2 Recombinant Protein (Animal Free) Lyophilized from Innovative Research has been recombinantly produced in E. coli. This is a Lyophilized protein buffered in with a purity of ? 98% by SDS-PAGE gel and HPLC analyses.
    
    Please contact us at for specific academic pricing.
    
    Background
    
    BMPs (Bone Morphogenetic Proteins) belong to the TGF-? superfamily of structurally related signaling proteins. BMP-2 is a potent osteoinductive cytokine, capable of inducing bone and cartilage formation in association with osteoconductive carriers such as collagen and synthetic hydroxyapatite. In addition to its osteogenic activity, BMP-2 plays an important role in cardiac morphogenesis, and is expressed in a variety of tissues, including lung, spleen, brain, liver, prostate, ovary, and small intestine. The functional form of BMP-2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains linked by a single disulfide bond. Each BMP-2 monomer is expressed as the C-terminal part of a precursor polypeptide, which also contains a 23 amino acid signal sequence for secretion, and a 259 amino acid propeptide. After dimerization of this precursor, the covalent bonds between the propeptide (which is also a disulfide-linked homodimer) and the mature BMP-2 ligand are cleaved by a furin-type protease. Recombinant Human/Murine/Rat BMP-2 is a 26.0 kDa homodimeric protein consisting of two 115 amino acid polypeptide chains.
- Properties
  - Protein Name
    
    BMP2
    
    Source
    
    E. coli
    
    Type
    
    Animal Free Proteins
    
    Purification
    
    >98% by SDS-PAGE gel and HPLC analyses.
    
    Storage
    
    The recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted protein is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing the recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
    
    * These products are supplied for manufacturing, research and laboratory use only.

Human BMP-2 Recombinant Protein (Animal Free) Lyophilized

Human BMP-2 Recombinant Protein (Animal Free) Lyophilized

Background

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