HRAS Polyclonal Antibody (0.66 mg/mL) for WB, IHC, ELISA

HRAS Polyclonal Antibody (0.66 mg/mL) for WB, IHC, ELISA

Catalog Number:
A001508703RED
Mfr. No.:
RD253241A
Price:
$253
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      • Overview
        • Calculated MW: 21 kDa
          Observed MW: Refer to figures
          Gene Accession: NP001123914

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          Background

          This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Synthetic peptide of human HRAS
          Purification
          Antigen affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          0.66 mg/mL
          Antigen
          C BAS/HAS, c H ras, C HA RAS1, c has/bas p21 protein, c ras Ki 2 activated oncogene, c-H-ras, CTLO, GTP and GDP binding peptide B, GTPase HRas, N-terminally processed, H Ras 1, H RASIDX, H-Ras-1, Ha Ras, Ha Ras1 proto oncoprotein, Ha-Ras, HAMSV, Harvey rat sarcoma viral oncogene homolog, Harvey rat sarcoma viral oncoprotein, HRAS, HRAS1, K ras, N ras, p19 H RasIDX protein, p21ras, Ras family small GTP binding protein H Ras, RASH, RASH1, Transformation gene oncogene HAMSV, Transforming protein p21, v Ha ras Harvey rat sarcoma viral oncogene homolog, VH Ras, vHa RAS (UniProt:P01112)

          * For reference only.

      • Applications
        • Application
          WB; IHC; ELISA
        • Application Dilutions
          WB 1:500-1:2000
          IHC 1:25-1:50
          ELISA 1:5000-1:10000

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