HNRNPAB Recombinant Protein

HNRNPAB Recombinant Protein

Catalog Number:
P001415273ABE
Mfr. No.:
Abe32-3981
Price:
  • Size:
    10 µg
    Quantity:
    Add to Cart:
      • Overview
        • HNRNPAB Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 308 amino acids (1-285 a.a) and having a molecular mass of 33kDa. HNRNPAB is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Heterogeneous Nuclear Ribonucleoprotein A/B(HNRNPAB) is a member of the subfamily of ubiquitously expressed heterogeneousnuclear ribonucleoproteins(hnRNPs). The hnRNPs are produced by RNA polymerase II and are components oftheheterogeneous nuclear RNA (hnRNA) complexes. They are linked with pre-mRNAsin the nucleus and seem to influence pre-mRNA processing and further aspects ofmRNA metabolism and transport. Whereas all of the hnRNPs are present in the nucleus, some seem toshuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinctnucleic acid binding properties. HNRNPAB, which binds to one of the componentsof the multiprotein editosomecomplex, has two repeats of quasi-RRM (RNA recognition motif) domains that bindto RNAs. Among the diseases associated with HNRNPABare wells syndrome, and cystic fibrosis.

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      • Properties
        • Protein Name
          Heterogeneous Nuclear Ribonucleoprotein A/B, ABBP-1, ABBP1, APOBEC1-Binding Protein 1, HnRNP A/B, Apobec-1 Binding Protein 1, ApolipoproteinB MRNA Editing Enzyme, Catalytic Polypeptide 1-Binding Protein 1, HnRNP TypeA/B Protein.
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greater than 95.0% as determined by SDS-PAGE.
          Formulation
          HNRNPAB protein solution (0.25mg/ml) containing 30% glycerol and 1mM DTT.
          Storage
          Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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