Name: HLA-DRA Recombinant Protein
Price: Inquiry

- Overview
  - HLA-DRA Human Recombinant produced in E. Coli is a single,non-glycosylated polypeptide chain containing 212 amino acids (26-216 a.a) andhaving a molecular mass of 24.3kDa. HLA-DRA is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Major histocompatibility complex, class II, DR alpha (HLA-DRA) belongsto the MHC class II family. HLA-DRA binds peptides derived from antigens whichaccess the endocytic route of antigen presenting cells (APC) and presents themon the cell surface for identification by the CD4 T-cells. The peptide bindingcleft accommodates peptides of 10-30 residues. The peptides presented by MHCclass II molecules are generated mainly by degradation of proteins which accessthe endocytic route, where they are processed by lysosomal proteases and otherhydrolases.
    
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- Properties
  - Protein Name
    
    Major Histocompatibility Complex, Class II, DR Alpha, HLA-DRA1, MHC Class II AntigenDRA, MLRW, Histocompatibility AntigenHLA-DRAlpha, HLAClass II Histocompatibility Antigen, DR Alpha Chain, MHC CellSurface Glycoprotein, HLA-DRA1.
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greaterthan 90% as determined by SDS-PAGE.
    
    Formulation
    
    HLA-DRA protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.
    
    Storage
    
    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

HLA-DRA Recombinant Protein

HLA-DRA Recombinant Protein

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