Name: HLA-DQB2 Polyclonal Antibody (1.26 mg/mL) for IHC, ELISA
Price: 253.00 USD

Overview
- Gene Accession: BC031995
  
  Please contact us at for specific academic pricing.
  
  Background
  
  HLA-DQB2 belongs to the family of HLA class II beta chain paralogs. Class II molecules are heterodimers consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. They play a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). Polymorphisms in the alpha and beta chains specify the peptide binding specificity, and typing for these polymorphisms is routinely done for bone marrow transplantation. However this gene, HLA-DQB2, is not routinely typed, as it is not thought to have an effect on transplantation. There is conflicting evidence in the literature and public sequence databases for the protein-coding capacity of HLA-DQB2. Because there is evidence of transcription and an intact ORF, HLA-DQB2 is represented in Entrez Gene and in RefSeq as a protein-coding locus.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human
  
  Immunogen
  
  Fusion protein of human HLA-DQB2
  
  Purification
  
  Antigen affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
  
  Storage
  
  Store at -20°C. Avoid freeze-thaw cycles.
  
  Concentration
  
  1.26 mg/mL
  
  Antigen
  
  DV19.1 (major histocompatibility complex, class II, DQ beta 2 (HLA-DXB)), DX-beta, HLA class II histocompatibility antigen, DQ beta 2 chain, HLA class II histocompatibility antigen, DX beta chain, HLA DQB1, HLA DXB, major histocompatibility complex, class II, DQ beta 1, Major histocompatibility complex, class II, DQ beta 2, Major histocompatibility complex, class II, DX beta, MHC class II antigen DQB2 (UniProt:P05538)
  
  * For reference only.

Applications

Application

IHC; ELISA

Application	Dilutions
IHC	1:50-1:200
ELISA	1:5000-1:10000

HLA-DQB2 Polyclonal Antibody (1.26 mg/mL) for IHC, ELISA

HLA-DQB2 Polyclonal Antibody (1.26 mg/mL) for IHC, ELISA

Background

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