HLA-DPA1 Polyclonal Antibody (0.96 mg/mL) for WB, IHC, ELISA

HLA-DPA1 Polyclonal Antibody (0.96 mg/mL) for WB, IHC, ELISA

Catalog Number:
A001506396RED
Mfr. No.:
RD218082A
Price:
$253
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      • Overview
        • Calculated MW: 29 kDa
          Observed MW: Refer to figures
          Gene Accession: NP291032

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          Background

          HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human
          Immunogen
          Synthetic peptide of human HLA-DPA1
          Purification
          Antigen affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          0.96 mg/mL
          Antigen
          DP(W3), DP(W4), HLA class II histocompatibility antigen DP alpha 1 chain, HLA class II histocompatibility antigen DP alpha chain , HLA DP1A, HLA DPA 1, HLA SB alpha chain, HLADP, HLADPA1 , HLASB, HLASB histocompatibility type, Human MHC class II HLA SB alpha gene, Major histocompatibility complex class II DP alpha 1, MHC class II antigen, MHC class II DP3 alpha, MHC class II DPA1, MHC class II HLA DPA1 antigen, PLT1, Primed lymphocyte test 1 (UniProt:P20036)

          * For reference only.

      • Applications
        • Application
          WB; IHC; ELISA
        • Application Dilutions
          WB 1:500-1:2000
          IHC 1:40-1:200
          ELISA 1:5000-1:10000

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