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Overview
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Calculated MW: 59kDa/70kDa/116kDa
Observed MW: 117kDaPlease contact us at for specific academic pricing.
Background
Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.
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- Properties
- Applications
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Overview