Name: HARS Recombinant Protein
Price: Inquiry

- Overview
  - Histidyl-tRNA Synthetase Human Recombinant produced in E. Coli is a single, non-glycosylated, polypeptide chain having a molecular mass of 55 kDa. Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis.
    
    Please contact us at for specific academic pricing.
- Properties
  - Protein Name
    
    Histidyl-tRNA synthetase, EC 6.1.1.21, Histidine-tRNA ligase, HisRS, HRS, FLJ20491, JO-1, HARS.
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greater than 95.0% as determined by both: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
    
    Formulation
    
    The protein solution contains 500mM NaCl and 10mM Tris (pH 8.0) and 6M Urea.
    
    Storage
    
    Histidyl-tRNA Synthetase although stable at 4°C for 3 weeks, should be stored below -18°C. Please prevent freeze-thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

HARS Recombinant Protein

HARS Recombinant Protein

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