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Overview
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Calculated MW: 43kDa/45kDa
Observed MW: 45kDaPlease contact us at for specific academic pricing.
Background
RNA-binding protein that plays a role in the regulation of transcription, pre-mRNA splicing and mRNA translation. Negatively regulates DNA-binding activity of the transcription factor MEF2C in myocardial cells in response to mechanical stress (By similarity. Plays a role in pre-mRNA splicing regulation. Binds (via C-terminus to poly(U RNA. Involved in mRNA translation regulation, probably at the initiation step. Seems to play a role in PML-nuclear bodies formation.
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- Properties
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Overview