Name: GRIK2 Polyclonal Antibody (1.56 mg/mL) for IHC, ELISA
Price: 253.00 USD

Overview
- Gene Accession: NP068775
  
  Please contact us at for specific academic pricing.
  
  Background
  
  GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2) is a Protein Coding gene. Diseases associated with GRIK2 include Autosomal Recessive Non-Syndromic Intellectual Disability and Spinocerebellar Ataxia 11. Among its related pathways are CREB Pathway and Presynaptic function of Kainate receptors. GO annotations related to this gene include protein homodimerization activity and ubiquitin protein ligase binding. An important paralog of this gene is GRIK3.Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Synthetic peptide of human GRIK2
  
  Purification
  
  Antigen affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
  
  Storage
  
  Store at -20°C. Avoid freeze-thaw cycles.
  
  Concentration
  
  1.56 mg/mL
  
  Antigen
  
  bA487F5.1, EAA4, Excitatory amino acid receptor 4, GLR 6, GLR6, GluK2, GLUK6, GLUR 6, GluR-6, GluR6, Glutamate receptor 6, Glutamate receptor, glutamate receptor form A, glutamate receptor form B, glutamate receptor form C, glutamate receptor form D, glutamate receptor form E, Glutamate receptor ionotropic kainate 2, GRIK 2, GRIK2, GRIK2 protein, GRIK2, ionotropic kainate 2, MRT6 (UniProt:Q13002)
  
  * For reference only.

Applications

Application

IHC; ELISA

Application	Dilutions
IHC	1:25-1:100
ELISA	1:5000-1:10000

GRIK2 Polyclonal Antibody (1.56 mg/mL) for IHC, ELISA

GRIK2 Polyclonal Antibody (1.56 mg/mL) for IHC, ELISA

Background

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